Note: This document pertains only to the antidotes contained in the antidote kit. Many other antidotes exist: if information is required, contact the poison centre at 1-800-565-8161
| Poison | Antidote |
|---|---|
| Acetaminophen | Acetylcysteine |
| Anesthetics, local | Lipid emulsion (Fat Emulsion) |
| Aniline | Methylene blue |
| Anticholinesterases (i.e. organophosphates) | Atropine, Pralidoxime (2-PAM) |
| Antidepressants, Cyclic (TCAs) | Sodium bicarbonate, Lipid emulsion |
| Antidepressants, noncyclic (i.e., SSRIs, SNRIs, bupropion, venlafaxine, etc) | Sodium bicarbonate, Lipid emulsion |
| Arsenic | Dimaval |
| Benzodiazepines | Flumazenil |
| Beta-blockers | Atropine, Insulin, Calcium, Glucagon (adjunctive therapy only), Lipid emulsion |
| Black Widow spider | Black Widow spider antivenin (Antivenin Latrodectus Mactans) |
| Calcium channel blockers | Atropine, Insulin, Calcium, Lipid emulsion |
| Cyanide | Hydroxocobalamin (Cyanokit), Sodium thiosulfate |
| Digoxin | Atropine, Digoxin immune Fab |
| Ethylene glycol | Fomepizole, Pyridoxine, Sodium bicarbonate |
| Glycol Ethers | Fomepizole |
| Hydrofluoric acid burns | Calcium gluconate |
| Iron | Deferoxamine (Desferrioxamine) |
| Isoniazid | Pyridoxine |
| Lead | Dimaval |
| Mercury (inorganic or elemental) | Dimaval |
| Methanol | Fomepizole |
| Mushrooms, Hepatotoxic (i.e., Amanita phalloides) | Acetylcysteine |
| Mushrooms, Seizure-inducing (gyromitra or hydrazine-containing mushrooms) | Pyridoxine |
| Nitrates | Methylene blue |
| Nitrites | Methylene blue |
| Opioids | Naloxone |
| Organophosphate insecticides | Atropine Pralidoxime (2-PAM) |
| Salicylates | Sodium bicarbonate |
| Sodium channel blocking drugs* (wide QRS) | Sodium bicarbonate, Lipid emulsion |
| Sulfonylurea (oral hypoglycaemic) | Octreotide |